PS3 | 3-Channel Peptide Synthesizer | Gyros Protein Technologies

Discontinued

Replacement Instrument - PurePep® Chorus

Self-installed Benchtop Peptide Synthesizer

The original reliable, versatile “plug’n play”
3-channel peptide synthesizer

Three reaction vessels
Standard or custom program
Fluid delivery
Supports Fmoc and t-Boc chemistries

Features

Applications

Specifications

Chemicals

Resources

Publications

Features

Three reaction vessels

Typical cycle times are under 40 minutes per coupling. Three reaction vessels let you synthesize up to three completely different peptides sequentially without operator attention. PS3 will perform up to 45 couplings automatically, without reloading or user intervention. Set it up to run overnight or over a weekend, for maximum productivity.

Standard or custom program

“Plug’n play” simplicity allows you to load vials in sequence and indicate what start and stop positions. Specify standard or custom program for each coupling, and push "RUN."

Fluid delivery

The zero-dead-volume fluid valve system has all PTFE wetted surfaces and just one moving part. A self-diagnostic program and multiple sensors ensure proper performance while a printer provides a permanent record of each synthesis. Fluid transfer and mixing are accomplished under inert atmospheres of nitrogen or argon.

Supports Fmoc and t-Boc chemistries

PS3 allows you to use a variety of coupling techniques: Fmoc-N-carboxyanhydride and Fmoc-acid fluoride chemistries can be performed without instrument modification. Different chemistries can be mixed in one synthesis. PS3 can also be used with either Fmoc or t-Boc protected amino acids. Pre-packaged reagents are available for 0.1 and 0.5 mmol synthesis scales. Coupling programs can be customized for special needs.

Looking for more information?

Request user manual

Applications

Peptide synthesis

All applications

Therapeutics and vaccines

Oncology peptide therapeutics

General research

Specifications

Number of reaction vessels	3, used sequentially
Synthesis scale range	0.005 – 1.5 mmol (at 2x excess)
Number of solvent positions/sizes	2 x 4 L primary solvent 1 x 1 L deprotectant 1 x 1 L base
Number of amino acid positions	5 amino acid vials, 5 mL capacity Pre-packaged vials available 0.4 mmol, 1.0 mmol scales
Chemistries supported	Fmoc, t-Boc, organic, others
Activation	HBTU, HATU, HCTU, TBTU, PyBOP, others
Throughput	User defined
Fluid measurement technique	Timed delivery, conformed with optical sensors
Fluid transfer method	Positive pressure with nitrogen Top-down washing
Agitation method	Nitrogen bubbling
Cleavage	Off instrument
Waste container	One 20 L container
Control interface	On-board CPU, LCD display and keyboard Preset and user programmable coupling conditions Manual operation, cleaning procedures
Reporting	Direct output to external printer (printer included on 115 V units only)
Power	115 V/60 Hz or 230 V/50 Hz
Dimensions (W x D x H)	32" x 21" x 19.5" (81 cm x 53 cm x 49 cm)
Weight	Approximately 51 lbs. (23 kg)
Warranty	One year, parts and labor

Chemicals

PurePep Reagents

Reagents

Resins

Your peptide synthesis needs are important to us. If you would like custom packaging, or other special handling conditions please send us your request here peptides@gyrosproteintech.com

Resources

Looking for technical documentation and references?

Find more technical documentation on our products as well as scientific references in our resource library. Learn about the ways our customers are using our products in research applications and peptide development.

Resource library