Gyrolab^® Generic Cyno ADA Kit Reagents

NEW Gyrolab^® Generic Cyno ADA Kit Reagents measure anti-drug antibodies as circulating immune complexes of human IgG in complex with cyno IgG on Gyrolab systems.

• Gyrolab Generic Cyno ADA Kit Reagents are ordered as a bundle that contains capture and detection reagents with sufficient volume for approximately 480 data points, sample dilution buffer, and wash buffer. 
• Gyrolab Bioaffy 1000 CDs* are purchased separately; all bundle components can also be ordered separately.

The generic nature of the Gyrolab Generic Cyno ADA Kit Reagents favors its use in early preclinical studies for ADA screening of therapeutic antibody candidates for unexpected PK, clearance profiles, safety, or efficacy issues caused by the formation of immune complexes.  A generic assay eliminates the need for assay optimization across molecules thereby streamlining preclinical development.

*Kit Reagents also provide assay flexibility for use with other Gyrolab Bioaffy CD types (requiring assay development).

GRAPH: A typical example of a serially diluted Cyno Positive Control in Rexxip H detected using the Gyrolab Generic Cyno ADA Kit Reagents and the Gyrolab Bioaffy 1000 CD.