The history of the Gyrolab platform

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    History

More than 20 years ago, we introduced the groundbreaking Gyrolab CD-based technology at DDT in Boston. Today, our proprietary high-performance nanoliter-scale immunoassay platforms, Gyrolab xPand and Gyrolab xPlore, are used by scientists in leading pharmaceutical, biotech, CRO, and CMO companies worldwide.

Applications include bioanalytical pharmacokinetics/pharmacodynamics, immunogenicity, biomarkers, and for bioprocess, affinity, product titer and quantitation of bioprocess-related impurities.

Our Innovation Timeline

history-1988-1999
1988-1999

Amersham Pharmacia Biotech

Project on miniaturization and microfluidics.

1988-1999
history-2000
2000

Gyros AB formed

Spin off from Amersham Pharmacia Biotech.

2000
history-2002
2002

Gyrolab Maldi SP1

First instrument for purifying protein samples for analysis by MALDI MS.

2002
history-2003
2003

Gyrolab Workstation and Bioaffy 200 CD

First immunoassay system for nanoliter-scale protein quantification launched at DDT in Boston.

2003
history-2006
2006

Cambridge Antibody Technologies purchases first system

Now Medimmune, Cambridge Antibody Technologies purchases first system for use in biotherapeutic development. Download Case Study: "One Mouse, One PK... the Magic of Capillary Microsampling and Gyrolab."

Download
2006
Gyrolab xP open
2009

Gyrolab xP launched

5-CD Gyrolab xP system launched with software designed for 21 CFR Part 11 compliance and extended validation support.

2009
history-2011
2011

Launch of ADA Solution

New Mixing CD 96 and software for analysis of anti-drug antibodies in serum for preclinical and clinical studies.

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2011
history-2014
2014

Gyrolab Protein A Kit launched

Gyrolab Protein A Kit launched to Protein A ligand impurities in bioprocess samples.
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2014
history-2015
2015

Gyrolab xPlore launched

Gyrolab xPlore, a single-CD, compact alternative to the Gyrolab xP launched.

Gyrolab CHO-HCP and huIgG Titer Kits launched to expand the bioprocess kit menu.

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2015
history-2016
2016

Gyrolab Affinity Software launched

Gyrolab Affinity Software module launched for in-solution affinity measurement.

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2016
logo-history

Gyros Protein Technologies formed

Gyros Protein Technologies was formed by the merger of Gyros AB and Protein Technologies, Inc., expanding offerings with the peptide synthesizers product line.

history-2017
2017

Continued kit launches and updates

  • Gyrolab Generic PK Kit
  • New ADA Solution
  • Updated Protein A Kit
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2017
history-2018
2018

Launch of Gyrolab xPand

  • Cooling of samples and reagents
  • Mix and match methods/CDs in a single run
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2018
history-2019
2019

Expansion of bioprocess kit offerings

  • Gyrolab E. coli HCP Kit
  • Gyrolab CHO HCP E3G Kit
  • Gyrolab p24 Kit
  • Gyrolab Bioaffy 1000 HC Assay Toolbox
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2019
Acquisition of Gyros Protein Technologies by Mesa Laboratories, Inc. in 2019

Acquisition of Gyros Protein Technologies by Mesa Laboratories, Inc.

Gyros Protein Technologies is now a Division of Mesa Laboratories, Inc.
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history-2020
2020

Gyrolab® AAVX Titer Kit launched

Kit to accelerate AAV vector titer measurement in 8 serotypes with 10x less samples launched.

Gyrolab® Bioaffy™ 1000 HC
Improved performance for low-affinity reagents.

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2020
history-2021
2021

Gyrolab® Bioaffy™ 4000 CD; Solutions for Gyrolab with Cygnus Technologies Inc.

Gyrolab Bioaffy 4000 CD launched for increased immunoassay sensitivity.

Ready to use Solutions for Gyrolab® in collaboration with Cygnus Technologies, Inc. for use with the Gyrolab technology.

HEK 293 HCP Solution for Gyrolab®, EndonucleaseGTP® Solution for Gyrolab®, and CHO HCP 3G Solution for Gyrolab® launched

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2021
history 2022
2022

Launch of Rexxip Scouting Pack; Gyrolab Human Cytokine Biomarker kits

Rexxip™ Scouting Pack

5 mL of Rexxip A, AN, H, HN, HX enable quick buffer screening in assay development

Gyrolab Human Cytokine Kit Reagents

Gyrolab cytokine kit reagents for quantification of human IL-4, IL-6, IL-10, IFN-gamma and TNF-alpha to low pg/mL levels were launched as a new category of biomarker assay kits.

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2022
Gyrolab 2G Generic PK Kit Reagents
2023

Launch of New Gyrolab Kits

Gyrolab 2G Generic PK Kit Reagents
Gyrolab 2G Generic PK Kit offers improved sensitivity for quantification of human therapeutic antibodies.

Gyrolab Generic Cyno ADA Kit Reagents
First-to-market kit for the generic detection of circulating immune complexes of human IgG with cynomolgus monkey (cyno) anti-human IgG.

Gyrolab PLBL2 Kit
For safe and efficient CHO monoclonal antibody development.

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2023
Gyrolab 20 years

Celebrating 20 Years Gyrolab Technology

2023 marks the 20-year anniversary of the first commercial introduction of the Gyrolab Workstation with microfluidic CD immunoassay technology, launched at the DDT conference.

 

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2024 kit launches
2024

Launch of new Gyrolab immunogenicity and biomarker Kits

Gyrolab Mouse Cytokine Kits
For quantification of murine TNF-alpha, IFN-gamma, IL-6, IL-10, and IL-4. Sensitive, robust, and automated  assays.

Gyrolab Generic Rodent ADA Kit Reagents
For the detection of circulating immune complexes of human IgG therapeutic with rodent (mouse or rat)  anti-human IgG ADAs.

Gyrolab Generic Anti-AAV Kit
Gyrolab Generic Anti-AAV Kit enables detection of anti-AAV antibodies in human and cynomolgus monkey matrices.

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2024